Breast Pathology

Papillary lesion of biopsy

The term of verrucous pigmented lesions includes a series of non-melanocytic and melanocytic, benign and malignant lesions. Among these, the most frequent is the seborrheic keratosis, a common epidermal tumor, affecting the papillary lesion of biopsy exposed areas of adult.

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In this work we present the clinical and dermoscopical aspects of three cases of verrucous pigmented lesions two seborrheic keratoses and one seborrheic keratosis-like melanoma that determined the diagnostic algorithm as well as the therapeutic approach. The above-presented cases underline the importance of dermatoscopy to determine the malignant potential of the pigmented lesions, the final appropriate treatment being possible after the histopathologic confirmation.

Dermatoscopia este o tehnică extrem de utilă în diagnosticarea leziunilor pigmentate cutaneo-mucoase, permiţând papillary lesion of biopsy leziunilor posibil maligne.

Leziunile pigmentate verucoase necesită o evaluare atentă, deoarece alături de leziuni benigne precum keratozele seboreice, nevii melanocitari, includ şi melanomul verucos. În acest articol sunt prezentate aspectele clinice şi dermatoscopice care au stat la baza diagnosticării a trei leziuni pigmentate verucoase cutanate.

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Influenţa datelor clinice asupra interpretării parametrilor dermatoscopici este un fapt incontestabil, fapt observat şi în cele două cazuri de keratoză seboreică prezentate, ambele încadrate eronat ca leziuni melanocitare nev verucos, respectiv melanom. În primul caz prezentat, vârsta pacientei şi aprecierea inexactă a duratei de evoluţie au condus spre diagnosticul de nev verucos, deşi parametrii dermatoscopici erau specifici keratozei seboreice.

În al doilea caz de keratoză seboreică confirmată histopatologic, amplitudinea aspectelor clinice de melanom au făcut ca examinatorul să identifice parametrii dermatoscopici compatibili cu diagnosticul de melanom, ignorându-i pe cei specifici keratozei seboreice. Cazul de melanom prezentat în acest articol clinic a mimat o keratoză seboreică, iar imaginea dermatoscopică a prezentat doar trăsături subtile specifice melanomului.


În toate cele trei cazuri prezentate dermatoscopia a identificat leziunile ca posibil maligne şi a impus biopsia excizională pentru precizarea diagnosticului şi papillary lesion of biopsy conduitei terapeutice adecvate. Facultas Verlags papillary lesion of biopsy Buchhandels. Vienna, Google Scholar 2.

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Not all lesions with a verrucous surface are seborrheic keratoses. J Am Acad Dermatol.

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Web of Science Crossref Google Scholar 3. Dermoscopy features of melanoma incognito: indications for biopsy.

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Crossref Web of Science Google Scholar 4. Melanoma: when dermoscopy is a pitfall. International Journal of Dermatology. Crossref Google Scholar 5.

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Epithelial keratin and filaggrin expression in seborrheic keratosis: evaluation based on histopathological classification. International Journal of Dermatology, ; 53 6 — Web of Science Crossref Google Scholar 6. Benign Epithelial Tumors, Hamartomas, and Hyperplasias.

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Cloudy and starry milia-like cysts: how well do they distinguish seborrheic keratoses from malignant melanomas?. J Eur Acad Dermatol Venereol.

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Crossref Web of Science Google Scholar 8. Diagnostic pitfalls of using dermoscopic features to differentiate between malignant melanoma and pigmented seborrhoeic keratosis.

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Google Scholar Pathology of melanoma: interpretation and new concepts. In: Cancer of the Skin; 2nd, Elsevier, WANG S.


The dermoscopic patterns of melanoma and non-melanoma skin cancer. What can hide under exophytic verrucous appearance?

Unfortunately, it does not have specific signs and symptoms, being associated with an aggressive evolution and a poor prognosis if left untreated. Their results suggest that Papillary lesion of biopsy and PD-L1 could be potential biomarkers for targeted treatment in some patients diagnosed with diffuse large B-cell lymphoma. Malignant lymphomas of the head and neck may raise therapeutic difficulties. OIU, Vlad D. In the last five years from 1st of January to 31st of Decemberwe noticed 6 cases of rectal cancer, developed in patients who underwent stoma reversal more than two years before, for different pathologies.

Web of Science Crossref Google Scholar Melanoma within the seborrheic keratosis. Dermatol Surg.

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Verrucous melanoma: differences and similarities between primary and secondary form. Dermatología Argentina, ; 15 2